It is very important for women who are trying to conceive to take a folic acid supplement for at least 3 months prior to conception up until the 12th week of pregnancy. Folic acid is the synthetic form of folate (or vitamin B9). This vitamin plays an important role in DNA formation, red blood cells, and nerve function. During pregnancy, a deficiency of folic acid can increase the risk of a baby developing a spinal issue called a neural tube defect, such as spina bifida. 400 micrograms of folic acid per day, although some women may be advised by their GP to take up to 5mg of folic acid per day depending on their medical history. Some women may need to take a methylated or active form of folate supplement if they have a specific mutation on the MTHFR gene which impacts folate absorption. Folate should also be consumed in the diet, this can be found in broccoli, Brussel sprouts, green leafy vegetables, legumes, and fortified products.

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